SATURDAY, SEPTEMBER 19 (bold = printed in bold in source)
| Matchup | Location | TV/Stream | Time |
|---|---|---|---|
| Lincoln (MO) vs. Quincy | Quincy, IL | GLVCN | 1p |
| Virginia State vs. Eliz. City State | Eliz. City, NC | CIAASN | 1p |
| Lincoln (PA) vs. Shaw | Durham, NC | CIAASN | 1p |
| Fayetteville State vs. J.C. Smith | Charlotte, NC | CIAASN | 1p |
| Benedict vs. Fort Valley State | Fort Valley, GA | ESPN+ | 1p |
| Reinhardt vs. Florida Memorial | Miami Gardens, FL | 1p | |
| W. Va. Wesleyan vs. W. Va. State | Institute, WV | MECDN | 1p |
| Albany State vs. Allen | Columbia, SC | SIACN | 2p |
| Saginaw Valley State vs. Kentucky State | Frankfort, KY | 2p | |
| Central State vs. Arkansas-Pine Bluff | Pine Bluff, AR | SWAC TV | 4p |
| Morehouse vs. Lane | Jackson, TN | 4p | |
| Hampton vs. Norfolk State | Norfolk, VA | ESPN+ | 4p |
| Va.-Lynchburg vs. Bethune-Cookman (HC) | D. Beach, FL | SWACTV | 4p |
| Bowie State vs. Alabama A&M | Huntsville, AL | SWAC TV | 6p |
| Tuskegee vs. Jackson State | Jackson, MS | SWAC TV | 6p |
| Delta State vs. Miss. Valley State | Itta Bena, MS | SWAC TV | 6p |
| La. Christian vs. Southern | Baton Rouge, LA | SWAC TV | 6p |
| Alcorn State vs. North Alabama | Florence, AL | ESPN+ | 6p |
| Texas College vs. Langston | Langston, OK | 6p | |
| Morgan State vs. Towson | Towson, MD | FloSports | 6p |
| N. C. Central vs. Gardner-Webb | Boiling Springs, NC | ESPN+ | 6p |
| Bluefield State vs. Virginia Union | Richmond, VA | 6p | |
| Winston-Salem State vs. Livingstone | Salisbury, NC | 6p | |
| Savannah State vs. Edward Waters | Jacksonville, FL | SIACN | 6p |
| Miles vs. Clark Atlanta | Atlanta, GA | SIACN | 6p |
| N. C. A&T vs. Campbell | Buies Creek, NC | FloCollege | 6p |
| Stephen F. Austin vs. Prairie View A&M | Pr. View, TX | SWAC TV | 7p |
| Tenn. State vs. Florida A&M | Tallahassee, FL | HBCUGO.tv | 7p |
| Delaware State vs. South Florida | Tampa, FL | ESPN+ | 7p |
| South Carolina State vs. Furman | Greenville, SC | ESPN+ | 7p |
